Endometriosis affects more than 265 million women, roughly one in ten of reproductive age. Yet it remains one of the most misunderstood, under‑researched and stigmatized conditions in modern medicine.\n\n“End of the Cycle,” a documentary presented by The Endometriosis Collective, seeks to change that conversation. Directed by Sammy Jaye and Soraya Simi, the film weaves personal narratives, cutting‑edge science, historical insights and cultural commentary, showing both suffering and the resilience, action and hope that follow.\n\nThe cast includes comedian Amy Schumer, Olympian Brittany Brown, actress Janel Parrish, musician Fọlákẹ́ Olówòfóyèkù, dancer Julianne Hough and filmmaker Sammy Jaye Lang, who each summed the disease in three words: agony, isolation, harmful. The film also revisits the 20th‑century icon Marilyn Monroe’s struggle with the condition.\n\nMIT Professor Linda Griffith appears to share her research and personal journey, emphasizing that understanding normal tissue regulation is essential to decipher diseased tissue and urging interdisciplinary collaboration for treatments and prevention. On September 30, MIT hosted Menstruation Science Day, gathering over 250 students, faculty, industry partners and patients for a screening and an expert panel that examined the state of women’s‑health innovation and what is needed to accelerate progress. Panelists included Sammy Jaye Lang, Steve Palmer of Baylor College of Medicine, MIT’s Eliezer Calo, obstetrician‑gynecologist Stephanie Morris of Newton‑Wellesley Hospital, and Aleshia Carlsen‑Bryan of MIT Health. The 1‑hour‑21‑minute film aims to challenge misconceptions, spur research and improve care.\n\nReview